How CF affects the liver

CF affects so much more than just the lungs - although this is definitely what it is most well known for.

Here we look at how it affects the liver.

CF can cause the blockage of small ducts in the liver which can lead to CF-related liver disease. CF related liver disease is caused by mucus building up and blocking bile ducts in the liver. This prevents bile from leaving the liver, which causes inflammation and produces scarring (fibrosis). This happens in about 5-10% of people with CF and is tested for every year at a person’s CF annual review. It can be managed by drugs, but it is a serious health risk and can require a liver transplant.